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            GFAP Mouse mAb
            EM1059
            規(guī)格: 價格:
            50μL ¥1280.00
            100μL ¥1980.00

            Overview

            Product name: GFAP Mouse mAb
            Reactivity: Rat, Mouse
            Alternative Names: Glial Fibrillary Acidic Protein ;Intermediate Filament Protein
            Source: Mouse
            Dilutions: WB 1:2,000-5,000 IHC 1:200-500
            Immunogen: Synthetic Peptide
            Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
            Clonality: Monoclonal
            Isotype: IgG1
            Concentration: 1mg/mL
            Observed Band: 45kDa
            GeneID: 2670
            Human Swiss-Prot No: P14136
            Cellular localization: Cytoplasm. Associated with intermediate filaments
            Background: GFAP is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
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