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            CDX2  Mouse mAb
            
                    EM1057
                    
            
                        
            
                            
            
                                規(guī)格：
                                價格：
                            
            
                                                        
            
                                50μL
                                ￥1280.00
                            
            
                                                        
            
                                100μL
                                ￥1980.00
                            
            
                                                    
            
                    
            
                    
                
            
            
            
        
            

                
            
            
            
                
            Overview
                    
            
                
            
                    
            
                        
            
                            
            
                                
            
                                    
            
                                        Product name:
                                        CDX2  Mouse mAb
                                    
            
                                                                            
            
                                            Reactivity:
                                            Human, Rat, Mouse
                                        
            
                                                                                
            
                                            Alternative Names:
                                            Caudal Type Homeobox Transcription Factor 2 ;CDX3; Homeobox Protein CDX-2
                                        
            
                                                                                
            
                                           Source:
                                           Mouse
                                           
                                        
            
                                                                                
            
                                           Dilutions:
                                           WB 1:1,000 IHC 1:200
                                           
                                        
            
                                                                                
            
                                           Immunogen:
                                           Synthetic Peptide
                                           
                                        
            
                                                                                
            
                                           Storage:
                                           PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
                                           
                                        
            
                                                                                
            
                                           Clonality:
                                           Monoclonal
                                           
                                        
            
                                                                                
            
                                           Isotype:
                                           IgG1
                                           
                                        
            
                                                                                
            
                                           Concentration:
                                           1mg/mL
                                           
                                        
            
                                                                                
            
                                           Observed Band:
                                           42kDa
                                           
                                        
            
                                                                                
            
                                           GeneID:
                                           1045
                                           
                                        
            
                                                                                
            
                                           Human Swiss-Prot No:
                                           Q99626
                                           
                                        
            
                                                                                
            
                                           Cellular localization:
                                           Nucleus
                                           
                                        
            
                                                                                
            
                                           Background:
                                           CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.
                                           
                                        
            
                                                                        
            
                            
            
                                                    
            
                    
            
                
            
            
            
                        
                    
            
    
            
    




            
    
            
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